Tenecteplase
Brand names,
Tenecteplase
Analogs
Tenecteplase
Brand Names Mixture
- Camoprima Infatabs (amodiaquine + primaquine)
Tenecteplase
Chemical_Formula
C2561H3919N747O781S40
Tenecteplase
RX_link
http://www.rxlist.com/cgi/generic2/tenecteplase.htm
Tenecteplase
fda sheet
Tenecteplase
msds (material safety sheet)
Tenecteplase
Synthesis Reference
No information avaliable
Tenecteplase
Molecular Weight
58951.2
Tenecteplase
Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Tenecteplase
H2O Solubility
No information avaliable
Tenecteplase
State
Liquid
Tenecteplase
LogP
-0.528
Tenecteplase
Dosage Forms
Powder for solution; Solution (IV injection)
Tenecteplase
Indication
For treatment of myocardial infarction and lysis of intracoronary emboli
Tenecteplase
Pharmacology
Cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
Tenecteplase
Absorption
No information avaliable
Tenecteplase
side effects and Toxicity
No information avaliable
Tenecteplase
Patient Information
No information avaliable
Tenecteplase
Organisms Affected
Humans and other mammals