Reteplase
Brand names,
Reteplase
Analogs
Reteplase
Brand Names Mixture
Reteplase
Chemical_Formula
C1736H2671N499O522S22
Reteplase
RX_link
http://www.rxlist.com/cgi/generic2/reteplase.htm
Reteplase
fda sheet
Reteplase
msds (material safety sheet)
Reteplase
Synthesis Reference
No information avaliable
Reteplase
Molecular Weight
39589.6
Reteplase
Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Reteplase
H2O Solubility
No information avaliable
Reteplase
State
Liquid
Reteplase
LogP
-0.435
Reteplase
Dosage Forms
Solution (IV injection); Powder for solution
Reteplase
Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
Reteplase
Pharmacology
Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
Reteplase
Absorption
No information avaliable
Reteplase
side effects and Toxicity
No information avaliable
Reteplase
Patient Information
No information avaliable
Reteplase
Organisms Affected
Humans and other mammals