t- PA
t- PA Brand names, t- PA Analogs
t- PA Brand Names Mixture
- No information avaliable
t- PA Chemical_Formula
C1736H2671N499O522S22
t- PA RX_link
http://www.rxlist.com/cgi/generic2/reteplase.htm
t- PA fda sheet
t- PA msds (material safety sheet)
t- PA Synthesis Reference
No information avaliable
t- PA Molecular Weight
39589.6
t- PA Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
t- PA H2O Solubility
No information avaliable
t- PA State
Liquid
t- PA LogP
-0.435
t- PA Dosage Forms
Solution (IV injection); Powder for solution
t- PA Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
t- PA Pharmacology
Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
t- PA Absorption
No information avaliable
t- PA side effects and Toxicity
No information avaliable
t- PA Patient Information
No information avaliable
t- PA Organisms Affected
Humans and other mammals
