t-plasminogen activator
t-plasminogen activator Brand names, t-plasminogen activator Analogs
t-plasminogen activator Brand Names Mixture
- No information avaliable
t-plasminogen activator Chemical_Formula
C1736H2671N499O522S22
t-plasminogen activator RX_link
http://www.rxlist.com/cgi/generic2/reteplase.htm
t-plasminogen activator fda sheet
t-plasminogen activator msds (material safety sheet)
t-plasminogen activator Synthesis Reference
No information avaliable
t-plasminogen activator Molecular Weight
39589.6
t-plasminogen activator Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
t-plasminogen activator H2O Solubility
No information avaliable
t-plasminogen activator State
Liquid
t-plasminogen activator LogP
-0.435
t-plasminogen activator Dosage Forms
Solution (IV injection); Powder for solution
t-plasminogen activator Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
t-plasminogen activator Pharmacology
Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
t-plasminogen activator Absorption
No information avaliable
t-plasminogen activator side effects and Toxicity
No information avaliable
t-plasminogen activator Patient Information
No information avaliable
t-plasminogen activator Organisms Affected
Humans and other mammals
