TNKase (Genentech Inc)
TNKase (Genentech Inc) Brand names, TNKase (Genentech Inc) Analogs
TNKase (Genentech Inc) Brand Names Mixture
- Camoprima Infatabs (amodiaquine + primaquine)
TNKase (Genentech Inc) Chemical_Formula
C2561H3919N747O781S40
TNKase (Genentech Inc) RX_link
http://www.rxlist.com/cgi/generic2/tenecteplase.htm
TNKase (Genentech Inc) fda sheet
TNKase (Genentech Inc) msds (material safety sheet)
TNKase (Genentech Inc) Synthesis Reference
No information avaliable
TNKase (Genentech Inc) Molecular Weight
58951.2
TNKase (Genentech Inc) Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
TNKase (Genentech Inc) H2O Solubility
No information avaliable
TNKase (Genentech Inc) State
Liquid
TNKase (Genentech Inc) LogP
-0.528
TNKase (Genentech Inc) Dosage Forms
Powder for solution; Solution (IV injection)
TNKase (Genentech Inc) Indication
For treatment of myocardial infarction and lysis of intracoronary emboli
TNKase (Genentech Inc) Pharmacology
Cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
TNKase (Genentech Inc) Absorption
No information avaliable
TNKase (Genentech Inc) side effects and Toxicity
No information avaliable
TNKase (Genentech Inc) Patient Information
No information avaliable
TNKase (Genentech Inc) Organisms Affected
Humans and other mammals
