Alteplase
Brand names,
Alteplase
Analogs
Alteplase
Brand Names Mixture
Alteplase
Chemical_Formula
C2569H3928N746O781S40
Alteplase
RX_link
http://www.rxlist.com/cgi/generic/alteplas.htm
Alteplase
fda sheet
Alteplase
msds (material safety sheet)
Alteplase
Synthesis Reference
No information avaliable
Alteplase
Molecular Weight
59042.3
Alteplase
Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Alteplase
H2O Solubility
No information avaliable
Alteplase
State
Liquid
Alteplase
LogP
-0.516
Alteplase
Dosage Forms
Powder for solution
Alteplase
Indication
For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
Alteplase
Pharmacology
Activase binds to fibrin in a thrombus and converts the entrapped plasminogen to plasmin. It also produces limited conversion of plasminogen in the absence of fibrin.
Alteplase
Absorption
No information avaliable
Alteplase
side effects and Toxicity
No information avaliable
Alteplase
Patient Information
BIOD00050.html
Alteplase
Organisms Affected
Humans and other mammals