Syntarpen
Brand names,
Syntarpen
Analogs
Syntarpen
Brand Names Mixture
Syntarpen
Chemical_Formula
C19H18ClN3O5S
Syntarpen
RX_link
No information avaliable
Syntarpen
fda sheet
Syntarpen
msds (material safety sheet)
Syntarpen
Synthesis Reference
No information avaliable
Syntarpen
Molecular Weight
435.882 g/mol
Syntarpen
Melting Point
No information avaliable
Syntarpen
H2O Solubility
13.9 mg/L
Syntarpen
State
Solid
Syntarpen
LogP
2.274
Syntarpen
Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
Syntarpen
Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Syntarpen
Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
Syntarpen
Absorption
Well absorbed from the gastrointestinal tract.
Syntarpen
side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
Syntarpen
Patient Information
Syntarpen
Organisms Affected
Enteric bacteria and other eubacteria