CXN
Brand names,
CXN
Analogs
CXN
Brand Names Mixture
CXN
Chemical_Formula
C19H18ClN3O5S
CXN
RX_link
No information avaliable
CXN
fda sheet
CXN
msds (material safety sheet)
CXN
Synthesis Reference
No information avaliable
CXN
Molecular Weight
435.882 g/mol
CXN
Melting Point
No information avaliable
CXN
H2O Solubility
13.9 mg/L
CXN
State
Solid
CXN
LogP
2.274
CXN
Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
CXN
Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
CXN
Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
CXN
Absorption
Well absorbed from the gastrointestinal tract.
CXN
side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
CXN
Patient Information
CXN
Organisms Affected
Enteric bacteria and other eubacteria