Methocillin S
Brand names,
Methocillin S
Analogs
Methocillin S
Brand Names Mixture
Methocillin S
Chemical_Formula
C19H18ClN3O5S
Methocillin S
RX_link
No information avaliable
Methocillin S
fda sheet
Methocillin S
msds (material safety sheet)
Methocillin S
Synthesis Reference
No information avaliable
Methocillin S
Molecular Weight
435.882 g/mol
Methocillin S
Melting Point
No information avaliable
Methocillin S
H2O Solubility
13.9 mg/L
Methocillin S
State
Solid
Methocillin S
LogP
2.274
Methocillin S
Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
Methocillin S
Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Methocillin S
Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
Methocillin S
Absorption
Well absorbed from the gastrointestinal tract.
Methocillin S
side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
Methocillin S
Patient Information
Methocillin S
Organisms Affected
Enteric bacteria and other eubacteria