Cloxapen
Cloxapen Brand names, Cloxapen Analogs
Cloxapen Brand Names Mixture
- No information avaliable
Cloxapen Chemical_Formula
C19H18ClN3O5S
Cloxapen RX_link
No information avaliable
Cloxapen fda sheet
Cloxapen msds (material safety sheet)
Cloxapen Synthesis Reference
No information avaliable
Cloxapen Molecular Weight
435.882 g/mol
Cloxapen Melting Point
No information avaliable
Cloxapen H2O Solubility
13.9 mg/L
Cloxapen State
Solid
Cloxapen LogP
2.274
Cloxapen Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
Cloxapen Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Cloxapen Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
Cloxapen Absorption
Well absorbed from the gastrointestinal tract.
Cloxapen side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
Cloxapen Patient Information
Cloxapen Organisms Affected
Enteric bacteria and other eubacteria
