Cloxacillin sodium
Brand names,
Cloxacillin sodium
Analogs
Cloxacillin sodium
Brand Names Mixture
Cloxacillin sodium
Chemical_Formula
C19H18ClN3O5S
Cloxacillin sodium
RX_link
No information avaliable
Cloxacillin sodium
fda sheet
Cloxacillin sodium
msds (material safety sheet)
Cloxacillin sodium
Synthesis Reference
No information avaliable
Cloxacillin sodium
Molecular Weight
435.882 g/mol
Cloxacillin sodium
Melting Point
No information avaliable
Cloxacillin sodium
H2O Solubility
13.9 mg/L
Cloxacillin sodium
State
Solid
Cloxacillin sodium
LogP
2.274
Cloxacillin sodium
Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
Cloxacillin sodium
Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Cloxacillin sodium
Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
Cloxacillin sodium
Absorption
Well absorbed from the gastrointestinal tract.
Cloxacillin sodium
side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
Cloxacillin sodium
Patient Information
Cloxacillin sodium
Organisms Affected
Enteric bacteria and other eubacteria