Sulfoxone
Sulfoxone Brand names, Sulfoxone Analogs
Sulfoxone Brand Names Mixture
- No information avaliable
Sulfoxone Chemical_Formula
C14H16N2O6S3
Sulfoxone RX_link
No information avaliable
Sulfoxone fda sheet
Sulfoxone msds (material safety sheet)
Sulfoxone Synthesis Reference
No information avaliable
Sulfoxone Molecular Weight
404.485 g/mol
Sulfoxone Melting Point
No information avaliable
Sulfoxone H2O Solubility
No information avaliable
Sulfoxone State
Solid
Sulfoxone LogP
-1.064
Sulfoxone Dosage Forms
Tablet
Sulfoxone Indication
For the treatment of leprosy and dermatitis herpetiformis
Sulfoxone Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfoxone Absorption
Rapidly absorbed.
Sulfoxone side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Sulfoxone Patient Information
Sulfoxone Organisms Affected
Enteric bacteria and other eubacteria
