Sodium Aldesulphone
Sodium Aldesulphone Brand names, Sodium Aldesulphone Analogs
Sodium Aldesulphone Brand Names Mixture
- No information avaliable
Sodium Aldesulphone Chemical_Formula
C14H16N2O6S3
Sodium Aldesulphone RX_link
No information avaliable
Sodium Aldesulphone fda sheet
Sodium Aldesulphone msds (material safety sheet)
Sodium Aldesulphone Synthesis Reference
No information avaliable
Sodium Aldesulphone Molecular Weight
404.485 g/mol
Sodium Aldesulphone Melting Point
No information avaliable
Sodium Aldesulphone H2O Solubility
No information avaliable
Sodium Aldesulphone State
Solid
Sodium Aldesulphone LogP
-1.064
Sodium Aldesulphone Dosage Forms
Tablet
Sodium Aldesulphone Indication
For the treatment of leprosy and dermatitis herpetiformis
Sodium Aldesulphone Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sodium Aldesulphone Absorption
Rapidly absorbed.
Sodium Aldesulphone side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Sodium Aldesulphone Patient Information
Sodium Aldesulphone Organisms Affected
Enteric bacteria and other eubacteria
