Diasone Sodium
Brand names,
Diasone Sodium
Analogs
Diasone Sodium
Brand Names Mixture
Diasone Sodium
Chemical_Formula
C14H16N2O6S3
Diasone Sodium
RX_link
No information avaliable
Diasone Sodium
fda sheet
Diasone Sodium
msds (material safety sheet)
Diasone Sodium
Synthesis Reference
No information avaliable
Diasone Sodium
Molecular Weight
404.485 g/mol
Diasone Sodium
Melting Point
No information avaliable
Diasone Sodium
H2O Solubility
No information avaliable
Diasone Sodium
State
Solid
Diasone Sodium
LogP
-1.064
Diasone Sodium
Dosage Forms
Tablet
Diasone Sodium
Indication
For the treatment of leprosy and dermatitis herpetiformis
Diasone Sodium
Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Diasone Sodium
Absorption
Rapidly absorbed.
Diasone Sodium
side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Diasone Sodium
Patient Information
Diasone Sodium
Organisms Affected
Enteric bacteria and other eubacteria