Novotrone
Novotrone Brand names, Novotrone Analogs
Novotrone Brand Names Mixture
- No information avaliable
Novotrone Chemical_Formula
C14H16N2O6S3
Novotrone RX_link
No information avaliable
Novotrone fda sheet
Novotrone msds (material safety sheet)
Novotrone Synthesis Reference
No information avaliable
Novotrone Molecular Weight
404.485 g/mol
Novotrone Melting Point
No information avaliable
Novotrone H2O Solubility
No information avaliable
Novotrone State
Solid
Novotrone LogP
-1.064
Novotrone Dosage Forms
Tablet
Novotrone Indication
For the treatment of leprosy and dermatitis herpetiformis
Novotrone Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Novotrone Absorption
Rapidly absorbed.
Novotrone side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Novotrone Patient Information
Novotrone Organisms Affected
Enteric bacteria and other eubacteria
