Sulfinpyrazone
Brand names,
Sulfinpyrazone
Analogs
Sulfinpyrazone
Brand Names Mixture
Sulfinpyrazone
Chemical_Formula
C23H20N2O3S
Sulfinpyrazone
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Sulfinpyrazone
fda sheet
Sulfinpyrazone
msds (material safety sheet)
Sulfinpyrazone
Synthesis Reference
No information avaliable
Sulfinpyrazone
Molecular Weight
404.483 g/mol
Sulfinpyrazone
Melting Point
136-137 oC
Sulfinpyrazone
H2O Solubility
31.2 mg/L
Sulfinpyrazone
State
Solid
Sulfinpyrazone
LogP
3.015
Sulfinpyrazone
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Sulfinpyrazone
Indication
For the treatment of gout and gouty arthritis.
Sulfinpyrazone
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Sulfinpyrazone
Absorption
No information avaliable
Sulfinpyrazone
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Sulfinpyrazone
Patient Information
No information avaliable
Sulfinpyrazone
Organisms Affected
Humans and other mammals