Sulfoxyphenylpyrazolidine
Brand names,
Sulfoxyphenylpyrazolidine
Analogs
Sulfoxyphenylpyrazolidine
Brand Names Mixture
Sulfoxyphenylpyrazolidine
Chemical_Formula
C23H20N2O3S
Sulfoxyphenylpyrazolidine
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Sulfoxyphenylpyrazolidine
fda sheet
Sulfoxyphenylpyrazolidine
msds (material safety sheet)
Sulfoxyphenylpyrazolidine
Synthesis Reference
No information avaliable
Sulfoxyphenylpyrazolidine
Molecular Weight
404.483 g/mol
Sulfoxyphenylpyrazolidine
Melting Point
136-137 oC
Sulfoxyphenylpyrazolidine
H2O Solubility
31.2 mg/L
Sulfoxyphenylpyrazolidine
State
Solid
Sulfoxyphenylpyrazolidine
LogP
3.015
Sulfoxyphenylpyrazolidine
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Sulfoxyphenylpyrazolidine
Indication
For the treatment of gout and gouty arthritis.
Sulfoxyphenylpyrazolidine
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Sulfoxyphenylpyrazolidine
Absorption
No information avaliable
Sulfoxyphenylpyrazolidine
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Sulfoxyphenylpyrazolidine
Patient Information
No information avaliable
Sulfoxyphenylpyrazolidine
Organisms Affected
Humans and other mammals