Sulfinpyrazon
Brand names,
Sulfinpyrazon
Analogs
Sulfinpyrazon
Brand Names Mixture
Sulfinpyrazon
Chemical_Formula
C23H20N2O3S
Sulfinpyrazon
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Sulfinpyrazon
fda sheet
Sulfinpyrazon
msds (material safety sheet)
Sulfinpyrazon
Synthesis Reference
No information avaliable
Sulfinpyrazon
Molecular Weight
404.483 g/mol
Sulfinpyrazon
Melting Point
136-137 oC
Sulfinpyrazon
H2O Solubility
31.2 mg/L
Sulfinpyrazon
State
Solid
Sulfinpyrazon
LogP
3.015
Sulfinpyrazon
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Sulfinpyrazon
Indication
For the treatment of gout and gouty arthritis.
Sulfinpyrazon
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Sulfinpyrazon
Absorption
No information avaliable
Sulfinpyrazon
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Sulfinpyrazon
Patient Information
No information avaliable
Sulfinpyrazon
Organisms Affected
Humans and other mammals