Sulfinpyrazine
Brand names,
Sulfinpyrazine
Analogs
Sulfinpyrazine
Brand Names Mixture
Sulfinpyrazine
Chemical_Formula
C23H20N2O3S
Sulfinpyrazine
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Sulfinpyrazine
fda sheet
Sulfinpyrazine
msds (material safety sheet)
Sulfinpyrazine
Synthesis Reference
No information avaliable
Sulfinpyrazine
Molecular Weight
404.483 g/mol
Sulfinpyrazine
Melting Point
136-137 oC
Sulfinpyrazine
H2O Solubility
31.2 mg/L
Sulfinpyrazine
State
Solid
Sulfinpyrazine
LogP
3.015
Sulfinpyrazine
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Sulfinpyrazine
Indication
For the treatment of gout and gouty arthritis.
Sulfinpyrazine
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Sulfinpyrazine
Absorption
No information avaliable
Sulfinpyrazine
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Sulfinpyrazine
Patient Information
No information avaliable
Sulfinpyrazine
Organisms Affected
Humans and other mammals