Diphenylpyrazone
Brand names,
Diphenylpyrazone
Analogs
Diphenylpyrazone
Brand Names Mixture
Diphenylpyrazone
Chemical_Formula
C23H20N2O3S
Diphenylpyrazone
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Diphenylpyrazone
fda sheet
Diphenylpyrazone
msds (material safety sheet)
Diphenylpyrazone
Synthesis Reference
No information avaliable
Diphenylpyrazone
Molecular Weight
404.483 g/mol
Diphenylpyrazone
Melting Point
136-137 oC
Diphenylpyrazone
H2O Solubility
31.2 mg/L
Diphenylpyrazone
State
Solid
Diphenylpyrazone
LogP
3.015
Diphenylpyrazone
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Diphenylpyrazone
Indication
For the treatment of gout and gouty arthritis.
Diphenylpyrazone
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Diphenylpyrazone
Absorption
No information avaliable
Diphenylpyrazone
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Diphenylpyrazone
Patient Information
No information avaliable
Diphenylpyrazone
Organisms Affected
Humans and other mammals