Sulphinpyrazone
Brand names,
Sulphinpyrazone
Analogs
Sulphinpyrazone
Brand Names Mixture
Sulphinpyrazone
Chemical_Formula
C23H20N2O3S
Sulphinpyrazone
RX_link
http://www.rxlist.com/cgi/generic3/sulfinpyrazone.htm
Sulphinpyrazone
fda sheet
Sulphinpyrazone
msds (material safety sheet)
Sulphinpyrazone
Synthesis Reference
No information avaliable
Sulphinpyrazone
Molecular Weight
404.483 g/mol
Sulphinpyrazone
Melting Point
136-137 oC
Sulphinpyrazone
H2O Solubility
31.2 mg/L
Sulphinpyrazone
State
Solid
Sulphinpyrazone
LogP
3.015
Sulphinpyrazone
Dosage Forms
100-mg tablets and 200-mg capsules for oral administration
Sulphinpyrazone
Indication
For the treatment of gout and gouty arthritis.
Sulphinpyrazone
Pharmacology
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Sulphinpyrazone
Absorption
No information avaliable
Sulphinpyrazone
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Sulphinpyrazone
Patient Information
No information avaliable
Sulphinpyrazone
Organisms Affected
Humans and other mammals