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Saquinavir Brand names, Saquinavir Analogs

Saquinavir Brand Names Mixture

  • No information avaliable

Saquinavir Chemical_Formula


Saquinavir RX_link

Saquinavir fda sheet

Saquinavir FDA

Saquinavir msds (material safety sheet)

Saquinavir Synthesis Reference

Parkes, Kevin E. B. et al., J. Org. Chem. 59(13) 3656-3664(1994)

Saquinavir Molecular Weight

670.841 g/mol

Saquinavir Melting Point

349.84 oC

Saquinavir H2O Solubility


Saquinavir State


Saquinavir LogP


Saquinavir Dosage Forms


Saquinavir Indication

For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.

Saquinavir Pharmacology

Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Saquinavir Absorption

Absolute bioavailability averages 4%

Saquinavir side effects and Toxicity

Probably experience pain in the throat

Saquinavir Patient Information

Saquinavir Organisms Affected

Human immunodeficiency virus