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Fortovase Brand names, Fortovase Analogs

Fortovase Brand Names Mixture

  • No information avaliable

Fortovase Chemical_Formula

C38H50N6O5

Fortovase RX_link

http://www.rxlist.com/cgi/generic/saquin.htm

Fortovase fda sheet

Fortovase FDA

Fortovase msds (material safety sheet)

Fortovase Synthesis Reference

Parkes, Kevin E. B. et al., J. Org. Chem. 59(13) 3656-3664(1994)

Fortovase Molecular Weight

670.841 g/mol

Fortovase Melting Point

349.84 oC

Fortovase H2O Solubility

Insoluble

Fortovase State

Solid

Fortovase LogP

3.645

Fortovase Dosage Forms

Capsules

Fortovase Indication

For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.

Fortovase Pharmacology

Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Fortovase Absorption

Absolute bioavailability averages 4%

Fortovase side effects and Toxicity

Probably experience pain in the throat

Fortovase Patient Information

Fortovase Organisms Affected

Human immunodeficiency virus