Fortovase
Fortovase Brand names, Fortovase Analogs
Fortovase Brand Names Mixture
- No information avaliable
Fortovase Chemical_Formula
C38H50N6O5
Fortovase RX_link
http://www.rxlist.com/cgi/generic/saquin.htm
Fortovase fda sheet
Fortovase msds (material safety sheet)
Fortovase Synthesis Reference
Parkes, Kevin E. B. et al., J. Org. Chem. 59(13) 3656-3664(1994)
Fortovase Molecular Weight
670.841 g/mol
Fortovase Melting Point
349.84 oC
Fortovase H2O Solubility
Insoluble
Fortovase State
Solid
Fortovase LogP
3.645
Fortovase Dosage Forms
Capsules
Fortovase Indication
For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.
Fortovase Pharmacology
Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
Fortovase Absorption
Absolute bioavailability averages 4%
Fortovase side effects and Toxicity
Probably experience pain in the throat
Fortovase Patient Information
Fortovase Organisms Affected
Human immunodeficiency virus
