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Invirase Brand names, Invirase Analogs

Invirase Brand Names Mixture

  • No information avaliable

Invirase Chemical_Formula

C38H50N6O5

Invirase RX_link

http://www.rxlist.com/cgi/generic/saquin.htm

Invirase fda sheet

Invirase FDA

Invirase msds (material safety sheet)

Invirase Synthesis Reference

Parkes, Kevin E. B. et al., J. Org. Chem. 59(13) 3656-3664(1994)

Invirase Molecular Weight

670.841 g/mol

Invirase Melting Point

349.84 oC

Invirase H2O Solubility

Insoluble

Invirase State

Solid

Invirase LogP

3.645

Invirase Dosage Forms

Capsules

Invirase Indication

For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.

Invirase Pharmacology

Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Invirase Absorption

Absolute bioavailability averages 4%

Invirase side effects and Toxicity

Probably experience pain in the throat

Invirase Patient Information

Invirase Organisms Affected

Human immunodeficiency virus