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Saquinavir Mesylate Brand names, Saquinavir Mesylate Analogs

Saquinavir Mesylate Brand Names Mixture

  • No information avaliable

Saquinavir Mesylate Chemical_Formula

C38H50N6O5

Saquinavir Mesylate RX_link

http://www.rxlist.com/cgi/generic/saquin.htm

Saquinavir Mesylate fda sheet

Saquinavir_Mesylate FDA

Saquinavir Mesylate msds (material safety sheet)

Saquinavir Mesylate Synthesis Reference

Parkes, Kevin E. B. et al., J. Org. Chem. 59(13) 3656-3664(1994)

Saquinavir Mesylate Molecular Weight

670.841 g/mol

Saquinavir Mesylate Melting Point

349.84 oC

Saquinavir Mesylate H2O Solubility

Insoluble

Saquinavir Mesylate State

Solid

Saquinavir Mesylate LogP

3.645

Saquinavir Mesylate Dosage Forms

Capsules

Saquinavir Mesylate Indication

For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.

Saquinavir Mesylate Pharmacology

Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Saquinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Saquinavir Mesylate Absorption

Absolute bioavailability averages 4%

Saquinavir Mesylate side effects and Toxicity

Probably experience pain in the throat

Saquinavir Mesylate Patient Information

Saquinavir Mesylate Organisms Affected

Human immunodeficiency virus