Ritodrine
Ritodrine Brand names, Ritodrine Analogs
Ritodrine Brand Names Mixture
- No information avaliable
Ritodrine Chemical_Formula
C17H21NO3
Ritodrine RX_link
No information avaliable
Ritodrine fda sheet
Ritodrine msds (material safety sheet)
Ritodrine Synthesis Reference
Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)
Ritodrine Molecular Weight
287.354 g/mol
Ritodrine Melting Point
88-90 oC
Ritodrine H2O Solubility
Complete
Ritodrine State
Solid
Ritodrine LogP
2.588
Ritodrine Dosage Forms
Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection
Ritodrine Indication
For the treatment and prophylaxis of premature labour
Ritodrine Pharmacology
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.
Ritodrine Absorption
No information avaliable
Ritodrine side effects and Toxicity
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
Ritodrine Patient Information
Ritodrine Organisms Affected
Humans and other mammals
