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Ritodrine Brand names, Ritodrine Analogs

Ritodrine Brand Names Mixture

  • No information avaliable

Ritodrine Chemical_Formula

C17H21NO3

Ritodrine RX_link

No information avaliable

Ritodrine fda sheet

Ritodrine msds (material safety sheet)

Ritodrine MSDS

Ritodrine Synthesis Reference

Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)

Ritodrine Molecular Weight

287.354 g/mol

Ritodrine Melting Point

88-90 oC

Ritodrine H2O Solubility

Complete

Ritodrine State

Solid

Ritodrine LogP

2.588

Ritodrine Dosage Forms

Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection

Ritodrine Indication

For the treatment and prophylaxis of premature labour

Ritodrine Pharmacology

Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.

Ritodrine Absorption

No information avaliable

Ritodrine side effects and Toxicity

LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)

Ritodrine Patient Information

Ritodrine Organisms Affected

Humans and other mammals