Ritodrine Hcl
Brand names,
Ritodrine Hcl
Analogs
Ritodrine Hcl
Brand Names Mixture
Ritodrine Hcl
Chemical_Formula
C17H21NO3
Ritodrine Hcl
RX_link
No information avaliable
Ritodrine Hcl
fda sheet
Ritodrine Hcl
msds (material safety sheet)
Ritodrine Hcl
Synthesis Reference
Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)
Ritodrine Hcl
Molecular Weight
287.354 g/mol
Ritodrine Hcl
Melting Point
88-90 oC
Ritodrine Hcl
H2O Solubility
Complete
Ritodrine Hcl
State
Solid
Ritodrine Hcl
LogP
2.588
Ritodrine Hcl
Dosage Forms
Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection
Ritodrine Hcl
Indication
For the treatment and prophylaxis of premature labour
Ritodrine Hcl
Pharmacology
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.
Ritodrine Hcl
Absorption
No information avaliable
Ritodrine Hcl
side effects and Toxicity
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
Ritodrine Hcl
Patient Information
Ritodrine Hcl
Organisms Affected
Humans and other mammals