Ritodrina
Ritodrina Brand names, Ritodrina Analogs
Ritodrina Brand Names Mixture
- No information avaliable
Ritodrina Chemical_Formula
C17H21NO3
Ritodrina RX_link
No information avaliable
Ritodrina fda sheet
Ritodrina msds (material safety sheet)
Ritodrina Synthesis Reference
Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)
Ritodrina Molecular Weight
287.354 g/mol
Ritodrina Melting Point
88-90 oC
Ritodrina H2O Solubility
Complete
Ritodrina State
Solid
Ritodrina LogP
2.588
Ritodrina Dosage Forms
Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection
Ritodrina Indication
For the treatment and prophylaxis of premature labour
Ritodrina Pharmacology
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.
Ritodrina Absorption
No information avaliable
Ritodrina side effects and Toxicity
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
Ritodrina Patient Information
Ritodrina Organisms Affected
Humans and other mammals
