Ritodrine Hydrochloride
Ritodrine Hydrochloride Brand names, Ritodrine Hydrochloride Analogs
Ritodrine Hydrochloride Brand Names Mixture
- No information avaliable
Ritodrine Hydrochloride Chemical_Formula
C17H21NO3
Ritodrine Hydrochloride RX_link
No information avaliable
Ritodrine Hydrochloride fda sheet
Ritodrine Hydrochloride msds (material safety sheet)
Ritodrine Hydrochloride Synthesis Reference
Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)
Ritodrine Hydrochloride Molecular Weight
287.354 g/mol
Ritodrine Hydrochloride Melting Point
88-90 oC
Ritodrine Hydrochloride H2O Solubility
Complete
Ritodrine Hydrochloride State
Solid
Ritodrine Hydrochloride LogP
2.588
Ritodrine Hydrochloride Dosage Forms
Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection
Ritodrine Hydrochloride Indication
For the treatment and prophylaxis of premature labour
Ritodrine Hydrochloride Pharmacology
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.
Ritodrine Hydrochloride Absorption
No information avaliable
Ritodrine Hydrochloride side effects and Toxicity
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
Ritodrine Hydrochloride Patient Information
Ritodrine Hydrochloride Organisms Affected
Humans and other mammals
