Ritodrinium
Ritodrinium Brand names, Ritodrinium Analogs
Ritodrinium Brand Names Mixture
- No information avaliable
Ritodrinium Chemical_Formula
C17H21NO3
Ritodrinium RX_link
No information avaliable
Ritodrinium fda sheet
Ritodrinium msds (material safety sheet)
Ritodrinium Synthesis Reference
Belg. pat. 660.244 (1965 to N.V. Philips), C.A. 63, 17965h (1965) corresp to Claassen et al., U.S. pat. 3,410,944 (1968 to No. Am. Philips)
Ritodrinium Molecular Weight
287.354 g/mol
Ritodrinium Melting Point
88-90 oC
Ritodrinium H2O Solubility
Complete
Ritodrinium State
Solid
Ritodrinium LogP
2.588
Ritodrinium Dosage Forms
Solution for IV; Capsule (extended-release); Tablet; Intramuscular injection
Ritodrinium Indication
For the treatment and prophylaxis of premature labour
Ritodrinium Pharmacology
Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.
Ritodrinium Absorption
No information avaliable
Ritodrinium side effects and Toxicity
LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)
Ritodrinium Patient Information
Ritodrinium Organisms Affected
Humans and other mammals
