Rhinotrop
Brand names,
Rhinotrop
Analogs
Rhinotrop
Brand Names Mixture
- Combivent Inhalation Aerosol (Ipratropium Bromide + Salbutamol Sulfate)
- Combivent Inhalation Solution (Ipratropium Bromide + Salbutamol Sulfate)
- Duovent Udv (Fenoterol Hydrobromide + Ipratropium Bromide)
- Ratio-Ipra Sal Udv (Ipratropium Bromide + Salbutamol Sulfate)
Rhinotrop
Chemical_Formula
C20H30NO3
Rhinotrop
RX_link
http://www.rxlist.com/cgi/generic/ipratrop.htm
Rhinotrop
fda sheet
Rhinotrop
msds (material safety sheet)
Rhinotrop
Synthesis Reference
K. Zeile et al.,U.S. Pat. 3,505,337 (1970)
Rhinotrop
Molecular Weight
332.457 g/mol
Rhinotrop
Melting Point
230-232oC
Rhinotrop
H2O Solubility
Freely soluble
Rhinotrop
State
Solid
Rhinotrop
LogP
No information avaliable
Rhinotrop
Dosage Forms
Aerosol (with propellants); Liquid; Metered-dose (aerosol); Metered-dose (pump); Solution
Rhinotrop
Indication
For maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
Rhinotrop
Pharmacology
Ipratropium bromide, a synthetic ammonium compound structurally similar to atropine, is used as a bronchodilator in the management of cholinergic-mediated bronchospasm associated with chronic obstructive pulmonary disease and in the treatment of rhinorrhea associated with the common cold or with allergic or nonallergic seasonal rhinitis.
Rhinotrop
Absorption
Inhalation (local)-minimal; Nasal-rapid and minimal
Rhinotrop
side effects and Toxicity
LD50=1001mg/kg (orally in mice)
Rhinotrop
Patient Information
Rhinotrop
Organisms Affected
Humans and other mammals