Ipatropium Bromide
Brand names,
Ipatropium Bromide
Analogs
Ipatropium Bromide
Brand Names Mixture
- Combivent Inhalation Aerosol (Ipratropium Bromide + Salbutamol Sulfate)
- Combivent Inhalation Solution (Ipratropium Bromide + Salbutamol Sulfate)
- Duovent Udv (Fenoterol Hydrobromide + Ipratropium Bromide)
- Ratio-Ipra Sal Udv (Ipratropium Bromide + Salbutamol Sulfate)
Ipatropium Bromide
Chemical_Formula
C20H30NO3
Ipatropium Bromide
RX_link
http://www.rxlist.com/cgi/generic/ipratrop.htm
Ipatropium Bromide
fda sheet
Ipatropium Bromide
msds (material safety sheet)
Ipatropium Bromide
Synthesis Reference
K. Zeile et al.,U.S. Pat. 3,505,337 (1970)
Ipatropium Bromide
Molecular Weight
332.457 g/mol
Ipatropium Bromide
Melting Point
230-232oC
Ipatropium Bromide
H2O Solubility
Freely soluble
Ipatropium Bromide
State
Solid
Ipatropium Bromide
LogP
No information avaliable
Ipatropium Bromide
Dosage Forms
Aerosol (with propellants); Liquid; Metered-dose (aerosol); Metered-dose (pump); Solution
Ipatropium Bromide
Indication
For maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
Ipatropium Bromide
Pharmacology
Ipratropium bromide, a synthetic ammonium compound structurally similar to atropine, is used as a bronchodilator in the management of cholinergic-mediated bronchospasm associated with chronic obstructive pulmonary disease and in the treatment of rhinorrhea associated with the common cold or with allergic or nonallergic seasonal rhinitis.
Ipatropium Bromide
Absorption
Inhalation (local)-minimal; Nasal-rapid and minimal
Ipatropium Bromide
side effects and Toxicity
LD50=1001mg/kg (orally in mice)
Ipatropium Bromide
Patient Information
Ipatropium Bromide
Organisms Affected
Humans and other mammals