Ipratropium Bromide
Brand names,
Ipratropium Bromide
Analogs
Ipratropium Bromide
Brand Names Mixture
- Combivent Inhalation Aerosol (Ipratropium Bromide + Salbutamol Sulfate)
- Combivent Inhalation Solution (Ipratropium Bromide + Salbutamol Sulfate)
- Duovent Udv (Fenoterol Hydrobromide + Ipratropium Bromide)
- Ratio-Ipra Sal Udv (Ipratropium Bromide + Salbutamol Sulfate)
Ipratropium Bromide
Chemical_Formula
C20H30NO3
Ipratropium Bromide
RX_link
http://www.rxlist.com/cgi/generic/ipratrop.htm
Ipratropium Bromide
fda sheet
Ipratropium Bromide
msds (material safety sheet)
Ipratropium Bromide
Synthesis Reference
K. Zeile et al.,U.S. Pat. 3,505,337 (1970)
Ipratropium Bromide
Molecular Weight
332.457 g/mol
Ipratropium Bromide
Melting Point
230-232oC
Ipratropium Bromide
H2O Solubility
Freely soluble
Ipratropium Bromide
State
Solid
Ipratropium Bromide
LogP
No information avaliable
Ipratropium Bromide
Dosage Forms
Aerosol (with propellants); Liquid; Metered-dose (aerosol); Metered-dose (pump); Solution
Ipratropium Bromide
Indication
For maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
Ipratropium Bromide
Pharmacology
Ipratropium bromide, a synthetic ammonium compound structurally similar to atropine, is used as a bronchodilator in the management of cholinergic-mediated bronchospasm associated with chronic obstructive pulmonary disease and in the treatment of rhinorrhea associated with the common cold or with allergic or nonallergic seasonal rhinitis.
Ipratropium Bromide
Absorption
Inhalation (local)-minimal; Nasal-rapid and minimal
Ipratropium Bromide
side effects and Toxicity
LD50=1001mg/kg (orally in mice)
Ipratropium Bromide
Patient Information
Ipratropium Bromide
Organisms Affected
Humans and other mammals