Atronase
Brand names,
Atronase
Analogs
Atronase
Brand Names Mixture
- Combivent Inhalation Aerosol (Ipratropium Bromide + Salbutamol Sulfate)
- Combivent Inhalation Solution (Ipratropium Bromide + Salbutamol Sulfate)
- Duovent Udv (Fenoterol Hydrobromide + Ipratropium Bromide)
- Ratio-Ipra Sal Udv (Ipratropium Bromide + Salbutamol Sulfate)
Atronase
Chemical_Formula
C20H30NO3
Atronase
RX_link
http://www.rxlist.com/cgi/generic/ipratrop.htm
Atronase
fda sheet
Atronase
msds (material safety sheet)
Atronase
Synthesis Reference
K. Zeile et al.,U.S. Pat. 3,505,337 (1970)
Atronase
Molecular Weight
332.457 g/mol
Atronase
Melting Point
230-232oC
Atronase
H2O Solubility
Freely soluble
Atronase
State
Solid
Atronase
LogP
No information avaliable
Atronase
Dosage Forms
Aerosol (with propellants); Liquid; Metered-dose (aerosol); Metered-dose (pump); Solution
Atronase
Indication
For maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
Atronase
Pharmacology
Ipratropium bromide, a synthetic ammonium compound structurally similar to atropine, is used as a bronchodilator in the management of cholinergic-mediated bronchospasm associated with chronic obstructive pulmonary disease and in the treatment of rhinorrhea associated with the common cold or with allergic or nonallergic seasonal rhinitis.
Atronase
Absorption
Inhalation (local)-minimal; Nasal-rapid and minimal
Atronase
side effects and Toxicity
LD50=1001mg/kg (orally in mice)
Atronase
Patient Information
Atronase
Organisms Affected
Humans and other mammals