Midazolam en es it fr

Midazolam Brand names, Midazolam Analogs

Midazolam Brand Names Mixture

  • No information avaliable

Midazolam Chemical_Formula


Midazolam RX_link


Midazolam fda sheet

Midazolam msds (material safety sheet)

Midazolam MSDS

Midazolam Synthesis Reference

No information avaliable

Midazolam Molecular Weight

325.767 g/mol

Midazolam Melting Point

159 oC

Midazolam H2O Solubility

40.0 mg/ml

Midazolam State


Midazolam LogP


Midazolam Dosage Forms

Liquid; Solution

Midazolam Indication

For use in pediatric patients for sedation, anxiolysis, and amnesia prior to diagnostic, therapeutic, or endoscopic procedures or before induction of anesthesia.

Midazolam Pharmacology

Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmacodynamic properties of midazolam and its metabolites, which are similar to those of other benzodiazepines, include sedative, anxiolytic, amnesic and hypnotic activities. Benzodiazepine pharmacologic effects appear to result from reversible interactions with the (gamma)-amino butyric acid (GABA) benzodiazepine receptor in the CNS, the major inhibitory neurotransmitter in the central nervous system. The action of midazolam is readily reversed by the benzodiazepine receptor antagonist, flumazenil.

Midazolam Absorption

Rapidly absorbed after oral administration (absolute bioavailability of the midazolam syrup in pediatric patients is about 36%, and intramuscular is greater than 90%).

Midazolam side effects and Toxicity

LD50=825 mg/kg (Orally in rats). Signs of overdose include sedation, somnolence, confusion, impaired coordination, diminished reflexes, coma, and deleterious effects on vital signs.

Midazolam Patient Information

Midazolam Organisms Affected

Humans and other mammals