Dormicum
Dormicum Brand names, Dormicum Analogs
Dormicum Brand Names Mixture
- No information avaliable
Dormicum Chemical_Formula
C18H13ClFN3
Dormicum RX_link
http://www.rxlist.com/cgi/generic2/versedsyr.htm
Dormicum fda sheet
Dormicum msds (material safety sheet)
Dormicum Synthesis Reference
No information avaliable
Dormicum Molecular Weight
325.767 g/mol
Dormicum Melting Point
159 oC
Dormicum H2O Solubility
40.0 mg/ml
Dormicum State
Solid
Dormicum LogP
3.868
Dormicum Dosage Forms
Liquid; Solution
Dormicum Indication
For use in pediatric patients for sedation, anxiolysis, and amnesia prior to diagnostic, therapeutic, or endoscopic procedures or before induction of anesthesia.
Dormicum Pharmacology
Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmacodynamic properties of midazolam and its metabolites, which are similar to those of other benzodiazepines, include sedative, anxiolytic, amnesic and hypnotic activities. Benzodiazepine pharmacologic effects appear to result from reversible interactions with the (gamma)-amino butyric acid (GABA) benzodiazepine receptor in the CNS, the major inhibitory neurotransmitter in the central nervous system. The action of midazolam is readily reversed by the benzodiazepine receptor antagonist, flumazenil.
Dormicum Absorption
Rapidly absorbed after oral administration (absolute bioavailability of the midazolam syrup in pediatric patients is about 36%, and intramuscular is greater than 90%).
Dormicum side effects and Toxicity
LD50=825 mg/kg (Orally in rats). Signs of overdose include sedation, somnolence, confusion, impaired coordination, diminished reflexes, coma, and deleterious effects on vital signs.
Dormicum Patient Information
Dormicum Organisms Affected
Humans and other mammals
