Midazolamum [Inn-Latin] en es it fr

Midazolamum [Inn-Latin] Brand names, Midazolamum [Inn-Latin] Analogs

Midazolamum [Inn-Latin] Brand Names Mixture

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Midazolamum [Inn-Latin] Chemical_Formula


Midazolamum [Inn-Latin] RX_link


Midazolamum [Inn-Latin] fda sheet

Midazolamum [Inn-Latin] msds (material safety sheet)

Midazolamum_[Inn-Latin] MSDS

Midazolamum [Inn-Latin] Synthesis Reference

No information avaliable

Midazolamum [Inn-Latin] Molecular Weight

325.767 g/mol

Midazolamum [Inn-Latin] Melting Point

159 oC

Midazolamum [Inn-Latin] H2O Solubility

40.0 mg/ml

Midazolamum [Inn-Latin] State


Midazolamum [Inn-Latin] LogP


Midazolamum [Inn-Latin] Dosage Forms

Liquid; Solution

Midazolamum [Inn-Latin] Indication

For use in pediatric patients for sedation, anxiolysis, and amnesia prior to diagnostic, therapeutic, or endoscopic procedures or before induction of anesthesia.

Midazolamum [Inn-Latin] Pharmacology

Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmacodynamic properties of midazolam and its metabolites, which are similar to those of other benzodiazepines, include sedative, anxiolytic, amnesic and hypnotic activities. Benzodiazepine pharmacologic effects appear to result from reversible interactions with the (gamma)-amino butyric acid (GABA) benzodiazepine receptor in the CNS, the major inhibitory neurotransmitter in the central nervous system. The action of midazolam is readily reversed by the benzodiazepine receptor antagonist, flumazenil.

Midazolamum [Inn-Latin] Absorption

Rapidly absorbed after oral administration (absolute bioavailability of the midazolam syrup in pediatric patients is about 36%, and intramuscular is greater than 90%).

Midazolamum [Inn-Latin] side effects and Toxicity

LD50=825 mg/kg (Orally in rats). Signs of overdose include sedation, somnolence, confusion, impaired coordination, diminished reflexes, coma, and deleterious effects on vital signs.

Midazolamum [Inn-Latin] Patient Information

Midazolamum [Inn-Latin] Organisms Affected

Humans and other mammals