Versed
Versed Brand names, Versed Analogs
Versed Brand Names Mixture
- No information avaliable
Versed Chemical_Formula
C18H13ClFN3
Versed RX_link
http://www.rxlist.com/cgi/generic2/versedsyr.htm
Versed fda sheet
Versed msds (material safety sheet)
Versed Synthesis Reference
No information avaliable
Versed Molecular Weight
325.767 g/mol
Versed Melting Point
159 oC
Versed H2O Solubility
40.0 mg/ml
Versed State
Solid
Versed LogP
3.868
Versed Dosage Forms
Liquid; Solution
Versed Indication
For use in pediatric patients for sedation, anxiolysis, and amnesia prior to diagnostic, therapeutic, or endoscopic procedures or before induction of anesthesia.
Versed Pharmacology
Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmacodynamic properties of midazolam and its metabolites, which are similar to those of other benzodiazepines, include sedative, anxiolytic, amnesic and hypnotic activities. Benzodiazepine pharmacologic effects appear to result from reversible interactions with the (gamma)-amino butyric acid (GABA) benzodiazepine receptor in the CNS, the major inhibitory neurotransmitter in the central nervous system. The action of midazolam is readily reversed by the benzodiazepine receptor antagonist, flumazenil.
Versed Absorption
Rapidly absorbed after oral administration (absolute bioavailability of the midazolam syrup in pediatric patients is about 36%, and intramuscular is greater than 90%).
Versed side effects and Toxicity
LD50=825 mg/kg (Orally in rats). Signs of overdose include sedation, somnolence, confusion, impaired coordination, diminished reflexes, coma, and deleterious effects on vital signs.
Versed Patient Information
Versed Organisms Affected
Humans and other mammals
