Letrozole
Letrozole Brand names, Letrozole Analogs
Letrozole Brand Names Mixture
- No information avaliable
Letrozole Chemical_Formula
C17H11N5
Letrozole RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Letrozole fda sheet
Letrozole msds (material safety sheet)
Letrozole Synthesis Reference
No information avaliable
Letrozole Molecular Weight
285.303 g/mol
Letrozole Melting Point
184-185 oC
Letrozole H2O Solubility
No information avaliable
Letrozole State
Solid
Letrozole LogP
3.385
Letrozole Dosage Forms
Tablet
Letrozole Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Letrozole Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Letrozole Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Letrozole side effects and Toxicity
No information avaliable
Letrozole Patient Information
No information avaliable
Letrozole Organisms Affected
Humans and other mammals
