Ketorolacum [Latin]
Brand names,
Ketorolacum [Latin]
Analogs
Ketorolacum [Latin]
Brand Names Mixture
Ketorolacum [Latin]
Chemical_Formula
C17H11N5
Ketorolacum [Latin]
RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Ketorolacum [Latin]
fda sheet
Ketorolacum [Latin]
msds (material safety sheet)
Ketorolacum [Latin]
Synthesis Reference
No information avaliable
Ketorolacum [Latin]
Molecular Weight
285.303 g/mol
Ketorolacum [Latin]
Melting Point
184-185 oC
Ketorolacum [Latin]
H2O Solubility
No information avaliable
Ketorolacum [Latin]
State
Solid
Ketorolacum [Latin]
LogP
3.385
Ketorolacum [Latin]
Dosage Forms
Tablet
Ketorolacum [Latin]
Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Ketorolacum [Latin]
Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Ketorolacum [Latin]
Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Ketorolacum [Latin]
side effects and Toxicity
No information avaliable
Ketorolacum [Latin]
Patient Information
No information avaliable
Ketorolacum [Latin]
Organisms Affected
Humans and other mammals