Acular
Acular Brand names, Acular Analogs
Acular Brand Names Mixture
- No information avaliable
Acular Chemical_Formula
C17H11N5
Acular RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Acular fda sheet
Acular msds (material safety sheet)
Acular Synthesis Reference
No information avaliable
Acular Molecular Weight
285.303 g/mol
Acular Melting Point
184-185 oC
Acular H2O Solubility
No information avaliable
Acular State
Solid
Acular LogP
3.385
Acular Dosage Forms
Tablet
Acular Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Acular Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Acular Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Acular side effects and Toxicity
No information avaliable
Acular Patient Information
No information avaliable
Acular Organisms Affected
Humans and other mammals
