Ketorolac Tromethamine
Brand names,
Ketorolac Tromethamine
Analogs
Ketorolac Tromethamine
Brand Names Mixture
Ketorolac Tromethamine
Chemical_Formula
C17H11N5
Ketorolac Tromethamine
RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Ketorolac Tromethamine
fda sheet
Ketorolac Tromethamine
msds (material safety sheet)
Ketorolac Tromethamine
Synthesis Reference
No information avaliable
Ketorolac Tromethamine
Molecular Weight
285.303 g/mol
Ketorolac Tromethamine
Melting Point
184-185 oC
Ketorolac Tromethamine
H2O Solubility
No information avaliable
Ketorolac Tromethamine
State
Solid
Ketorolac Tromethamine
LogP
3.385
Ketorolac Tromethamine
Dosage Forms
Tablet
Ketorolac Tromethamine
Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Ketorolac Tromethamine
Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Ketorolac Tromethamine
Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Ketorolac Tromethamine
side effects and Toxicity
No information avaliable
Ketorolac Tromethamine
Patient Information
No information avaliable
Ketorolac Tromethamine
Organisms Affected
Humans and other mammals