Acular LS
Brand names,
Acular LS
Analogs
Acular LS
Brand Names Mixture
Acular LS
Chemical_Formula
C17H11N5
Acular LS
RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Acular LS
fda sheet
Acular LS
msds (material safety sheet)
Acular LS
Synthesis Reference
No information avaliable
Acular LS
Molecular Weight
285.303 g/mol
Acular LS
Melting Point
184-185 oC
Acular LS
H2O Solubility
No information avaliable
Acular LS
State
Solid
Acular LS
LogP
3.385
Acular LS
Dosage Forms
Tablet
Acular LS
Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Acular LS
Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Acular LS
Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Acular LS
side effects and Toxicity
No information avaliable
Acular LS
Patient Information
No information avaliable
Acular LS
Organisms Affected
Humans and other mammals