Ketoralac
Brand names,
Ketoralac
Analogs
Ketoralac
Brand Names Mixture
Ketoralac
Chemical_Formula
C17H11N5
Ketoralac
RX_link
http://www.rxlist.com/cgi/generic2/letroz.htm
Ketoralac
fda sheet
Ketoralac
msds (material safety sheet)
Ketoralac
Synthesis Reference
No information avaliable
Ketoralac
Molecular Weight
285.303 g/mol
Ketoralac
Melting Point
184-185 oC
Ketoralac
H2O Solubility
No information avaliable
Ketoralac
State
Solid
Ketoralac
LogP
3.385
Ketoralac
Dosage Forms
Tablet
Ketoralac
Indication
For the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Ketoralac
Pharmacology
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumor tissue.
Ketoralac
Absorption
Rapidly and completely absorbed. Absorption is not affected by food.
Ketoralac
side effects and Toxicity
No information avaliable
Ketoralac
Patient Information
No information avaliable
Ketoralac
Organisms Affected
Humans and other mammals