Gyne lotrimin

Gyne lotrimin Brand names, Gyne lotrimin Analogs

Gyne lotrimin Brand Names Mixture

Lotrisone (clotrimazole + betamethasone)

Gyne lotrimin Chemical_Formula

C₂₂H₁₇ClN₂

Gyne lotrimin RX_link

http://www.rxlist.com/cgi/generic2/clotrimaz.htm

Gyne lotrimin fda sheet

Gyne_lotrimin FDA

Gyne lotrimin msds (material safety sheet)

Gyne_lotrimin MSDS

Gyne lotrimin Synthesis Reference

K. H. Buechel et al.; U.S. Pat. 4,705,172(1972)

Gyne lotrimin Molecular Weight

344.837 g/mol

Gyne lotrimin Melting Point

147-149 ^oC

Gyne lotrimin H₂O Solubility

29.84 mg/mL

Gyne lotrimin State

Solid

Gyne lotrimin LogP

5.98

Gyne lotrimin Dosage Forms

Cream; Liquid; Solution; Suppository; Ointment; Lozenge

Gyne lotrimin Indication

For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.

Gyne lotrimin Pharmacology

Clotrimazole, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Betamethasone and clotrimazole are used together to treat cutaneous tinea infections. In studies in fungal cultures, the minimum fungicidal concentration of clotrimazole caused leakage of intracellular phosphorous compounds into the ambient medium with concomitant breakdown of cellular nucleic acids, and accelerated potassium etflux. Both of these events began rapidly and extensively after addition of the drug to the cultures. The primary action of clotrimazole is against dividing and growing organisms.

Gyne lotrimin Absorption

Poorly and erratically absorbed orally, minimal vaginal or topical absorption.

Gyne lotrimin side effects and Toxicity

Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.

Gyne lotrimin Patient Information

How to use Clotrimazole :Use clotrimazole exactly as directed by your doctor. Always
read the manufacturer's information leaflet, if possible, before beginning treatment.
Clotrimazole preparations are usually applied two to three times a day until the
infection has cleared. This medicine is for you. Never give it to others, even if
their condition appears to be the same as yours. Getting the most from your
treatment : Always wash and dry your hands thoroughly before and after handling
clotrimazole. Do not allow clotrimazole to come into contact with the eyes, ears,
or mucous membranes (eg. mouth, vagina, inside of nose etc.), unless you are advised
to do so by your doctor. Complete the full course of treatment with clotrimazole,
otherwise your infection is likely to recur. Before using any 'over-the-counter'
medicines, check with your pharmacist which medicines are safe for you to use alongside
clotrimazole. You should see an improvement in your condition after a few days.
If your condition does not seem to be getting better after seven days, consult your
doctor for advice.

Gyne lotrimin Organisms Affected

Yeast and other fungi