Gevilon
Gevilon Brand names, Gevilon Analogs
Gevilon Brand Names Mixture
- No information avaliable
Gevilon Chemical_Formula
C15H22O3
Gevilon RX_link
http://www.rxlist.com/cgi/generic/gemfib.htm
Gevilon fda sheet
Gevilon msds (material safety sheet)
Gevilon Synthesis Reference
P. L. CREGER, U.S. Pat. 3,674,836 (1972)
Gevilon Molecular Weight
250.333 g/mol
Gevilon Melting Point
61-63 oC
Gevilon H2O Solubility
10 mg/mL (in base)
Gevilon State
Solid
Gevilon LogP
4.242
Gevilon Dosage Forms
Tablets; Capsules
Gevilon Indication
For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.
Gevilon Pharmacology
Gemfibrozil, a fibric acid antilipemic agent similar to clofibrate, is used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. It acts to reduce triglyceride levels, reduce VLDL levels, reduce LDL levels (moderately), and increase HDL levels (moderately).
Gevilon Absorption
Well absorbed from gastrointestinal tract (within 1-2 hours).
Gevilon side effects and Toxicity
Oral, mouse: LD50 = 3162 mg/kg. Symptoms of overdose include abdominal cramps, diarrhea, joint and muscle pain, nausea, and vomiting.
Gevilon Patient Information
Gemfibrozil is used to lower high triglyceride and cholesterol levels. Notify your physician if you are pregnant or nursing. Gemfibrozil should be taken 30 minutes before the morning and evening meals. This medication may cause dizziness or blurred vision; use caution while driving or operating hazardous machinery. Gemfibrozil may cause an increase in blood sugar. If you have diabetes mellitus, carefully monitor blood sugar levels. Notify your physician if you develop severe stomach pain, muscle pain or weakness, or unexplained fever.
Gevilon Organisms Affected
Humans and other mammals
