Apo-Gemfibrozil

Apo-Gemfibrozil Brand names, Apo-Gemfibrozil Analogs

Apo-Gemfibrozil Brand Names Mixture

No information avaliable

Apo-Gemfibrozil Chemical_Formula

C₁₅H₂₂O₃

Apo-Gemfibrozil RX_link

http://www.rxlist.com/cgi/generic/gemfib.htm

Apo-Gemfibrozil fda sheet

Apo-Gemfibrozil FDA

Apo-Gemfibrozil msds (material safety sheet)

Apo-Gemfibrozil Synthesis Reference

P. L. CREGER, U.S. Pat. 3,674,836 (1972)

Apo-Gemfibrozil Molecular Weight

250.333 g/mol

Apo-Gemfibrozil Melting Point

61-63 ^oC

Apo-Gemfibrozil H₂O Solubility

10 mg/mL (in base)

Apo-Gemfibrozil State

Solid

Apo-Gemfibrozil LogP

4.242

Apo-Gemfibrozil Dosage Forms

Tablets; Capsules

Apo-Gemfibrozil Indication

For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.

Apo-Gemfibrozil Pharmacology

Gemfibrozil, a fibric acid antilipemic agent similar to clofibrate, is used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. It acts to reduce triglyceride levels, reduce VLDL levels, reduce LDL levels (moderately), and increase HDL levels (moderately).

Apo-Gemfibrozil Absorption

Well absorbed from gastrointestinal tract (within 1-2 hours).

Apo-Gemfibrozil side effects and Toxicity

Oral, mouse: LD₅₀ = 3162 mg/kg. Symptoms of overdose include abdominal cramps, diarrhea, joint and muscle pain, nausea, and vomiting.

Apo-Gemfibrozil Patient Information

Gemfibrozil is used to lower high triglyceride and cholesterol levels. Notify your physician if you are pregnant or nursing. Gemfibrozil should be taken 30 minutes before the morning and evening meals. This medication may cause dizziness or blurred vision; use caution while driving or operating hazardous machinery. Gemfibrozil may cause an increase in blood sugar. If you have diabetes mellitus, carefully monitor blood sugar levels. Notify your physician if you develop severe stomach pain, muscle pain or weakness, or unexplained fever.

Apo-Gemfibrozil Organisms Affected

Humans and other mammals