PharmacyCodes



Fosfomycin en es it fr

Fosfomycin Brand names, Fosfomycin Analogs

Fosfomycin Brand Names Mixture

  • Micardis Plus (Hydrochlorothiazide + Telmisartan)

Fosfomycin Chemical_Formula

C3H7O4P

Fosfomycin RX_link

http://www.rxlist.com/cgi/generic2/fosfomycin.htm

Fosfomycin fda sheet

Fosfomycin FDA

Fosfomycin msds (material safety sheet)

Fosfomycin Synthesis Reference

No information avaliable

Fosfomycin Molecular Weight

138.059 g/mol

Fosfomycin Melting Point

94 oC

Fosfomycin H2O Solubility

50 mg/mL (Sodium salt)

Fosfomycin State

Solid

Fosfomycin LogP

-0.912

Fosfomycin Dosage Forms

Powder

Fosfomycin Indication

For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.

Fosfomycin Pharmacology

Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.

Fosfomycin Absorption

Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%

Fosfomycin side effects and Toxicity

LD50>5 g/kg (rats). Side effects may include diarrhea

Fosfomycin Patient Information

No information avaliable

Fosfomycin Organisms Affected

E. coli and other enteric bacteria