Monurol
Monurol Brand names, Monurol Analogs
Monurol Brand Names Mixture
- Micardis Plus (Hydrochlorothiazide + Telmisartan)
Monurol Chemical_Formula
C3H7O4P
Monurol RX_link
http://www.rxlist.com/cgi/generic2/fosfomycin.htm
Monurol fda sheet
Monurol msds (material safety sheet)
Monurol Synthesis Reference
No information avaliable
Monurol Molecular Weight
138.059 g/mol
Monurol Melting Point
94 oC
Monurol H2O Solubility
50 mg/mL (Sodium salt)
Monurol State
Solid
Monurol LogP
-0.912
Monurol Dosage Forms
Powder
Monurol Indication
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.
Monurol Pharmacology
Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
Monurol Absorption
Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%
Monurol side effects and Toxicity
LD50>5 g/kg (rats). Side effects may include diarrhea
Monurol Patient Information
No information avaliable
Monurol Organisms Affected
E. coli and other enteric bacteria
