Fosfomycin sodium

Fosfomycin sodium Brand names, Fosfomycin sodium Analogs

Fosfomycin sodium Brand Names Mixture

Micardis Plus (Hydrochlorothiazide + Telmisartan)

Fosfomycin sodium Chemical_Formula

C₃H₇O₄P

Fosfomycin sodium RX_link

http://www.rxlist.com/cgi/generic2/fosfomycin.htm

Fosfomycin sodium fda sheet

Fosfomycin_sodium FDA

Fosfomycin sodium msds (material safety sheet)

Fosfomycin sodium Synthesis Reference

No information avaliable

Fosfomycin sodium Molecular Weight

138.059 g/mol

Fosfomycin sodium Melting Point

94 ^oC

Fosfomycin sodium H₂O Solubility

50 mg/mL (Sodium salt)

Fosfomycin sodium State

Solid

Fosfomycin sodium LogP

-0.912

Fosfomycin sodium Dosage Forms

Powder

Fosfomycin sodium Indication

For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.

Fosfomycin sodium Pharmacology

Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.

Fosfomycin sodium Absorption

Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%

Fosfomycin sodium side effects and Toxicity

LD₅₀>5 g/kg (rats). Side effects may include diarrhea

Fosfomycin sodium Patient Information